SEROPREVALENCE AND COMPARISON BETWEEN METHODS OF SYPHILIS DETECTION AMONG BLOOD DONORS IN LAGOS STATE/NIGERIA

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SEROPREVALENCE AND COMPARISON BETWEEN METHODS OF SYPHILIS DETECTION AMONG BLOOD DONORS IN LAGOS STATE/NIGERIA

Abstract

This study was conducted among blood donors in Central Blood Bank of Lagos. On a total of ninety tow samples were collected, during the period from March to May 2018, to demonstrate the frequency of syphilis and to compare between different diagnostic methods for detection of syphilis. All samples were tested from ELISA, ICT and RPR. The seroprevalence of syphilis revealed from ELISA method was 7(7.6 %), which was equal to ICT but was slightly increase in RPR 8 (8.7%). The high frequency of syphilis 3 (42.9%) was found in both age group of (26-35and36-45). There was no positive cases between the ages of (46- 55) years. 5 (71.4%) of positive samples were seen among single blood donors, 2 (28.6%) among married donors and no positive cases among divorced blood donors. ICT method showed 100% sensitivity and 100% specificity. RPR showed 100% sensitivity and 98.8% specificity. Results showed that the ICT used in this study was the same when compared with ELISA but the RPR showed less specificity than ELISA . The study concluded that ICT with ELISA were the best methods for screening blood donors.

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