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COMPARISON OF FLUID PRELOAD AND COLOAD IN THE PREVENTION OF SPINAL ANAESTHESIA INDUCED HYPOTENSION DURING CAESAREAN SECTION
ABSTRACT
This prospective, randomized study compared the effectiveness of crystalloid preload
and crystalloid coload in the prevention of spinal anaesthesia-induced hypotension
during Caesarean section.
Eighty paturients with American Society of Anesthesiologists’ (ASA) physical status
1 or 2, with full term singleton pregnancy and scheduled to undergo lower segment
Caesarean section under spinal anaesthesia were randomly assigned into two
treatment groups. Group A received crystalloid preload of 20 ml/kg while group B
received a similar fluid load as coload. Patients’ haemodynamic changes, complaints
of nausea, episodes of retching/vomiting and vasopressor use, as well as neonatal
Apgar score, were recorded during the period of the procedure.
The incidence of hypotension in the preload and coload group in the pre-delivery
period were 35.0% and 26.3% (p = 0.690) while incidence of hypotension for the
entire procedure were 45.0% and 39.5% (p = 0.244) respectively. In the preload
group, 25% had complaints of nausea against 18.4% in the coload group (p = 0.495).
The incidence of retching/vomiting in the parturients and neonatal Apgar scores were
similar in both groups.
There was no difference in the incidence of spinal induced hypotension and spinal
induced hypotension related complications in the parturients following preloading or
co-loading.
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