MALARIAL HEPATOPATHY IN FALCIPARUM MALARIA

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MALARIAL HEPATOPATHY IN FALCIPARUM MALARIA

ABSTRACT

Jaundice is one of the common manifestations of severe Falciparium malaria but hepatitis is unusual. Although hepatic dysfunction is unusual and hepatic encephalopathy is almost never seen in malaria, yet, cases of hepatic dysfunction are being increasingly reported in patients with P. falciparium infection, from different parts of the world. The extent of hepatocellular dysfunction varies from mild abnormalities in liver function tests to hepatic failure. Patients with hepatocellular dysfunction in malaria are more prone to develop complications, but have a favorable outcome if hepatic involvement is recognized early and managed properly. It is important to meticulously look for hepatic dysfunction in patients with severe malaria, distinguish it from fulminant hepatic failure and manage it aggressively.

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